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As with every hormone, research shows melatonin levels typically decline with age. Melatonin levels begin to decline around age 30. Then, there is a significant decrease in melatonin levels after age 40, which accelerates as patients approach age 60.

Growing scientific data shows that melatonin supplementation can promote both improved sleep onset and maintenance in this patient population.† However, until recently, the delivery of exogenous melatonin in the body has not been fully optimized for this purpose.

Melatonin Formulations

Conventional immediate-release (IR) melatonin formulations on the market can improve sleep onset but fail to address sleep quality and maintenance due to melatonin’s short half-life. Also, timed-release melatonin formulations do not faithfully replicate the body’s own melatonin release profile.†

REMfresh’s patented Ion-Powered Pump™ (IPP) technology is scientifically designed to address these limitations by mimicking the body’s own melatonin release profile. It allows melatonin to be continuously released and absorbed throughout the intestinal tract for up to 7 hours.†

Melatonin Formulations

Learn more about REMfresh with our current REMfresh product information sheet.