Unlike other melatonin products, REMfresh’s patented technology releases melatonin continuously for up to 7 hours, mimicking the body’s natural release of melatonin.†
This may help you fall asleep faster, stay asleep longer†, and experience better quality sleep.†
REMfresh is not a prescription drug. It doesn’t contain narcotics, sedatives, antihistamines, or alcohol. REMfresh doesn’t cause morning drowsiness and isn’t associated with dependence or withdrawal symptoms.
REMfresh helps you wake up refreshed without a drug hangover effect.†
After you take REMfresh, there is an initial burst release of melatonin that helps you fall asleep.
The caplet gradually turns into a semi-solid gel matrix. This matrix keeps the melatonin bioavailable.
The concentration gradient within the matrix continuously pumps out melatonin for up to 7 hours.
This patented Ion-Powered Pump technology allows for Continuous Release and Absorption of ultrapure melatonin the same way the body naturally releases and maintains melatonin throughout the night.
REMfresh exceeded the targeted sleep maintenance threshold.1
In a study, 99.4 percent of patients indicated they were likely or very likely to continue taking REMfresh for their sleep issues.2
Over 5,000 physicians are recommending REMfresh.3
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At REMfresh, we understand just how important it is to provide our consumers with a product that is trusted not only by them, but by dozens of experts in the field of sleep science. REMfresh has been clinically tested and examined extensively over the years, making this melatonin sleep aid a reliable choice for individuals looking to treat their occasional sleeplessness and wake up feeling refreshed.
Other sleep supplement brands can’t say the same about their products. And it is not just the sleep specialists involved in REMfresh studies who endorse our supplement. We are continuously reaching out to doctors across the country through trade shows, sampling programs and direct mail to put our products in the hands of some of the country’s most influential physicians specializing in sleep.
In 2020, the IQVIA ProVoice Feb-March 2020 survey among primary care physicians with a certification in sleep disorders declared REMfresh as the #1 sleep doctor-recommended brand. REMfresh ranks for the third year as the #1 recommended modified-release melatonin brand, for the second year as the #1 recommended melatonin brand and for the first year as the #1 recommended non prescription sleep aid brand overall by primary care physicians with certification in sleep disorders.¹
The market for melatonin sleep supplements continues to grow, and there are products available for purchase that offer inflated claims but deliver unsubstantial results. While there are a lot of sleep aids available for purchase, REMfresh is the only modified-release melatonin product that is favored by board-certified sleep specialists throughout the nation. With REMfresh, you can feel safe about the choice you made for your melatonin supplement.
The clinical and real-world data behind REMfresh® is unprecedented for any melatonin product offered in the United States. REMfresh’s 7-hour innovation is supported by three lanes of clinical proof. First is the breakthrough 7-hour Pharmacokinetic Data (REMAKT), second is the depth of real-world patient-reported data found in REMVAL and REMSS, and finally the REMSU24 study, one of the few large-scale adverse event reports on melatonin that has been peer reviewed, which points to REMfresh’s outstanding safety profile.4
REMfresh’s patented Ion-Powered Pump™ technology releases high-quality melatonin continuously throughout the night, mimicking the body’s natural release profile.†
In some other products, melatonin release peaks after the first few hours of sleep and decreases sharply thereafter.
REMfresh’s release pattern of melatonin throughout the night resembles a mesa – a flat-topped hill with steep sides. It’s estimated that one-third of adults have occasional difficulty falling or staying asleep. This may be because their body is no longer producing this Mesa Wave™ pattern of melatonin release.